Hair loss treatment | Stony Brook Medicine

Regenerative medicine for treatment of hair loss – Exosome Therapy

Why are growth factors the new frontier in hair restoration and skin transformation?

A growth factor is a naturally occurring protein-substance that may be capable of stimulating cell proliferation (growth), healing, and occasionally cellular differentiation. Aesthetically, growth factors play an important role in maintaining skin firmness, tone, and elasticity and for local hair treatment, the vitality and hair revitalization that can only be achieved with the regenerative process propelled by high concentrations of exosomes.

Did You Know?

AFTER AGE 18, WE LOSE 1% OF COLLAGEN EVERY YEAR DUE TO OUR SKIN CELLS LOSING EFFICIENCY TO MAKE GROWTH FACTORS.

What are Exosomes?

Exosomes are nanoparticles that are released and received by nearly all cells in the body. They are typically 30-100 nm in size. These extracellular vesicles act as one of our body’s communication systems, delivering important molecular payloads from cell to cell. Each extracellular vesicle’s particular biological function is determined by molecules that reside either on its surface or in its interior and their known for their cell-cell information or intracellular communication; they are “messenger molecules”. The growth factors and mRNA contained in these vesicles communicate to other cells to change their behavior.

Did You Know?

Hair follicles age along with every other part of the human body though follicular cells are different than most other cells as they age with each growth cycle. Throughout each phase of the hair growth cycle (there are four distinct phases) the follicular cells miniaturize and the progressive brittleness of hair strands begins. This continues through each phase until growth desists.

JuveXO® Hair: Advancing Hair Aesthetics through Exosome Technology

The Science

JuveXO® H offers a novel approach in cosmetichair and scalp care, utilizing exosome technology derived from mesenchymal stem cells (MSCs) of umbilical cord tissue. Exosomes are nano-sized, bioactive messengers involved in cellular communication, delivering important proteins and growth factors that contribute to an optimal environment for hair aesthetics. JuveXO® H is carefully formulated with exosomes, growth factors, hyaluronic acid, and essential extracellular matrixproteins, such as types I and III collagen, making itan ideal product for non-invasive cosmetic hair treatments.

Revolutionizing Haircare with the Power of Exomes

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This advanced serum is distributed by CongelaBiocosmetics, LLC and complies with FDA cosmetic regulations, providing physicians with a reliable and consistent product for their aesthetic practices.

The H in haircare

Once practitioners and patients experienced theremarkable rejuvenating properties of JuveXO®,our scientific team posed the question – what about hair? By combining the powerful properties ofJuveXO® with proprietary recombinant proteinsspecifically designed for hair, JuveXO H targetscommon hair concerns to deliver more radiant hair.

Understanding Exosomes

Exosomes are extracellular vesicles involved in cellular communication, transferring proteins and other signaling molecules between cells. In cosmetic applications, exosomes derived from MSCs assist in the transportation of essential proteins, growth factors, and other components ideal for skin and hair. This contributes to the improved appearance of the scalp and hair.

By utilizing exosomes in JuveXO® H, physicians are provided with a cutting-edge topical serum designed to support and enhance the look of hair and scalp through non-invasive means.

JuveXO® H is composed of a proprietary blend of MSC-derived exosomes and complementary ingredients, including: Exosomes, Hyaluronic Acid, Amino Acids, Collagen (Types 1 & 3) and Glutathione.

Mechanisms of Action

JuveXO® H is applied topically to the scalp, delivering exosomes and other essential molecules to support the environment around the hair follicles. The inclusion of hyaluronic acid improves moisture retention, potentially contributing to a fuller, more hydrated appearance of hair. Collagen and amino acids in the formulation may help strengthen the hair's appearance, making it smoother and more resilient.

Manufacturing and Quality Control

JuveXO® H is manufactured in the United States under current Good Manufacturing Practices (cGMP) and complies with FDA cosmetic standards. Ethically sourced from umbilical cord tissue with informed consent, JuveXO® H is triple-filtered and processed under stringent quality controls to ensure product safety and consistency.

Platelet Rich Plasma (PRP) Injections for hair loss:

For many men and women, hair is an important linking factor of identity because it’s tied to one’s appearance. Loss of hair is often unexpected and can be traumatizing. Hair loss can be a function of various types of dermatologic hair disorders, autoimmune disorders or hair styling. Whether one’s hair is affected by changes in medications, health issues or decisions on how to wear one’s hair (options that create tension on hair follicles, excessively drying hair out etc.), the first step to address it is to seek an evaluation from a dermatologist. Some dermatologists specifically specialize in hair loss as their primary area of clinical interest and one can expect to have a biopsy and lab work-up to appropriately identify the specific type of hair disorder since many tend to mimic each other and can only be definitively diagnosed with testing.

The inherent benefits in using your own blood (Platelet Rich Plasma) is that it contains fundamental proteins containing growth factor. PRP treatment uses patented technology to spin down your blood isolating the growth factors in high concentration to inject into the hair follicles and stimulate hair growth. The epidermal growth factor in the plasma is essential to cell growth, reproduction, and differentiation during the hair follicle remodeling phase.